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Inflammation and Allergy In Vivo Models


| Pharmacology Discovery Services (Eurofins Discovery Partner Lab) 공식 대리점


Eurofins Discovery의 Pharmacology Discovery Services는 30년 이상의 in vivo testing 경험을 바탕으로 Inflammatory disease에 대한 Basic model 및 NASH, Fibrosis 등의 Inflammation-induced organ damage model 또한 제공합니다.


  • 관련 Biomarker (Cytokine) 및 생리학적 변화 주기적 관찰
  • 행동학적 변화 (scratching, mechanical allodynia, histopathology 등) 결과 제공
  • High-quality, Reproducible data
  • Dose-dependent manner
  • Approved benchmark positive control
  • Custom Model Development


Auto-Immune Disease*
Model Name Item Number Species
Arthritis, Adjuvant-Induced (AIA) 553010 Rat
Arthritis, Collagen mAb-Induced (CAIA) 553600 Mouse
Arthritis, Collagen-Induced (CIA) 553680 Mouse
Arthritis, Collagen-Induced (CIA) 553700 Rat
Diabetes, Type I, Streptozotocin-Induced 541000 Mouse
Diabetes, Type I, Streptozotocin-Induced 541010 Rat
Lupus, Systemic Lupus Erythematosus (SLE) 558000 Mouse
*Other auto-immune disease models include Inflammatory Bowel Disease (found under Digestive System) and Psoriasis (found under Dermal Inflammation).


Dermal Inflammation*
Model Name Item Number Species
Allergy, Passive Cutaneous Anaphylaxis (PCA) 503030 Mouse
Allergy, Passive Cutaneous Anaphylaxis (PCA) 503000 Rat
Dermatitis, Atopic, DNCB-Induced 555700 Mouse
Dermatitis, Atopic, MC930-Induced 555740 Mouse
Dermatitis, Atopic, Mite-Induced 555710 Mouse
Dermatitis, Contact, Arachidonic Acid-Induced 554010 Mouse
Dermatitis, Contact, Capsaicin-Induced 554310 Mouse
Dermatitis, Contact, Croton Oil-Induced 554510 Mouse
Dermatitis, Contact, Oxazolone-Induced 555510 Mouse
Dermatitis, Contact, Phorbol Ester-Induced 555010 Mouse
Inflammation, Acute Delayed-Type Hypersensitivity (DTH) 553200 Mouse
Inflammation, Chronic Delayed-Type Hypersensitivity (DTH) 553210 Mouse
Psoriasis, Topical, Imiquimod (IMQ)-Induced 555650 Mouse
Wound Healing, Skin 595000 Mouse
Wound Healing, Skin, db/db Mouse 595020 Mouse
*Other dermal inflammation disease models include Pruritus (found under CNS/Pain).


Digestive System
Model Name Item Number Species
Gastric Irritation 535020 Rat
Gastric Ulcers, Aspirin-Induced 535900 Rat
Gastric Ulcers, Ethanol-Induced 536000 Rat
Hepatic Injury, Acetaminophen (APAP)-Induced 546040 Mouse
Hepatic Injury, Carbon Tetrachloride (CCl4)-Induced 546000 Mouse
Hepatic Injury, Concanavalin A (Con-A)-Induced 546030 Mouse
Hepatic Injury, Liver Fibrosis, Bile Duct Ligation (BDL)-Induced 546090 Rat
Hepatic Injury, Liver Fibrosis, Chronic, Carbon Tetrachloride (CCI4) with Phenobarbial-Induced 546050 Rat
Hepatic Injury, Liver Fibrosis, Chronic, Carbon Tetrachloride (CCl4)-Induced 546060 Rat
Hepatic Injury, Nonalcoholic Steatohepatitis (NASH), CDAHFD Diet-Induced 546082 Mouse
Hepatic Injury, Nonalcoholic Steatohepatitis (NASH), MCD Diet-Induced 546080 Mouse
Inflammatory Bowel Disease (IBD), DNBS-Induced Colitis 553400 Rat
Inflammatory Bowel Disease (IBD), DSS-Induced Colitis 553420 Mouse
Inflammatory Bowel Disease (IBD), DSS-Induced Colitis 553425 Rat
Inflammatory Bowel Disease (IBD), Oxazolone-Induced Colitis 553430 Mouse
Inflammatory Bowel Disease (IBD), TNBS-Induced Colitis 553405 Mouse
Inflammatory Bowel Disease (IBD), TNBS-Induced Colitis 553410 Rat
Pancreatitis, Acute, Caerulein-Induced 566000 Mouse
Pancreatitis, Chronic, Caerulein-Induced 566100 Mouse


Respiratory System
Model Name Item Number Species
Asthma, Airway Hyperresponsiveness (AHR), Ovalbumin-Induced 568050 Mouse
Cough, Capsaicin-Induced 508850 Guinea pig
Cough, Citric Acid-Induced 508800 Guinea pig
Fibrosis, Lung, Bleomycin-Induced 568070 Mouse
Pulmonary, Lipopolysaccharide-Induced Neutrophilia 572100 Mouse
Pulmonary, Lipopolysaccharide-Induced Neutrophilia 572110 Rat


Model Name Item Number Species
Gout, Hyperuricemia, Potassium Oxonate-Induced 546600 Rat
Inflammation, Carrageenan-Induced 553510 Mouse
Inflammation, Carrageenan-Induced 553520 Rat


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