EPIscan Cell-based Assay 서비스
EPIscan Screening & Profiling 서비스는 Cell-based Bromodomain & Histone Methyltransferase (HMT) Assay로,
InCELL Hunter™ technology를 통해 세포 내 환경에서 Compound의 Permeability와 Binding을 직접적으로 측정할 수 있습니다.
Eurofins Discovery
| Eurofins Discover (Eurofins Discovery) 공식 대리점
INTRODUCTION
- Primary Screening, Lead Optimization, SAR 등의 다양한 Application에 이용 가능
- Cellular Potency에 따른 Compound의 Rank Ordering
- 재현 가능한 고품질의 데이터 생성을 통한 연구 시간 단축
서비스 종류 및 샘플 준비 방법
| 서비스 유형 | EPIscan |
| Assay Type | Cell-based Functional Assay |
| 실험농도 | 선택 가능 |
| 농도 개수 | 선택 가능 |
| 반복실험횟수 | Duplicate |
| Sample Volume | 실험할 농도의 1000X stock으로 40 uL |
| TAT | 15 Business Days |
서비스 상세
| Class | Assay Targets | Service | Product | |
| Item no. | Cell line | Kit | ||
| Writer | EHMT1 Human Histone Methyltransferase (HMT) Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2404AG | ||
| G9A Human Histone Methyltransferase (HMT) Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2403AG | O | O | |
| PRMT3 Human Protein Arginine N-Methyltransferase Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2393AG | O | ||
| Reader | BAZ2A Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2392AG | O | |
| BRD2 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2397AG | O | O | |
| BRD2 (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2394AG | O | ||
| BRD3 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2399AG | O | ||
| BRD3 (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2398AG | O | O | |
| BRD4 (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2400AG | O | O | |
| BRDT (1) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2402AG | O | ||
| BRDT (1,2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2401AG | O | O | |
| SMARCA4 Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2396AG | O | O | |
| TAF1L (2) Human Bromodomain-Containing Cell Based Agonist Binding LeadHunter Assay – US | 85-0001P-2395AG | O | ||
| Kinase | BLK Human TK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2441AG | O | O |
| BTK Human TK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2436AG | O | O | |
| CK1delta (CSNK1D) Human CK1 Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2433AG | O | O | |
| CLK1 Human CMGC Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2434AG | O | O | |
| CLK2 Human CMGC Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2435AG | O | O | |
| FGR Human TK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2442AG | O | ||
| HCK Human TK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2443AG | O | O | |
| MEK1 Human STE Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2444AG | O | O | |
| PI3Kdelta (PIK3CD) Human PtdIns(4,5)P 3-Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2439AG | O | ||
| Pim1 Human CAMK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2431AG | O | O | |
| PYK2 Human TK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2438AG | O | O | |
| RIPK1 Human TKL Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2430AG | O | ||
| RIPK2 Human TKL Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2440AG | O | O | |
| RIPK3 Human TKL Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2429AG | O | ||
| SIK Human CAMK Kinase Cell Based Agonist Binding LeadHunter Assay – US | 86-0022P-2432AG | O | O | |
| Apoptosis | B2CL1-BAX Human Pathways Cell Based Agonist Protein Binding LeadHunter Assay – US | 86-0016P-2648AG | O | O |
| B2CL1-BIM Human Pathways Cell Based Agonist Protein Binding LeadHunter Assay – US | 86-0016P-2649AG | O | ||
| BCL2-BAX Human Pathways Cell Based Agonist Protein Binding LeadHunter Assay – US | 86-0016P-2646AG | O | ||
| BCL2-BIM Human Pathways Cell Based Agonist Protein Binding LeadHunter Assay – US | 86-0016P-2647AG | O | ||
| MCL1-BIM Human Pathways Cell Based Agonist Protein Binding LeadHunter Assay – US | 86-0016P-2645AG | O | ||
Related Service
Related Product
InCELL Hunter™ Cell Line
Native 세포 환경에서 화합물 투과성 및 결합을 직접 측정할 수 있도록 하는 Cell Line으로, Intracellular Binding에 대한 데이터를 얻을 수 있습니다.
| Cell Background | Target | Cat. No. |
| A549 | EP300 Bromodomain | 96-0073C15 |
| G9a Methyltransferase | 96-0003C15 | |
| GLP Methyltransferase | 96-0045C15 | |
| PRMT3 Methyltransferase | 96-0072C15 | |
| HEK 293 | BAZ2A Bromodomain | 96-0074C1 |
| BRD2(1,2) Bromodomain | 96-0049C1 | |
| BRD2(1) Bromodomain | 96-0004C1 | |
| BRD3(1,2) Bromodomain | 96-0038C1 | |
| BRD3(1) Bromodomain | 96-0036C1 | |
| BRD4(1) Bromodomain | 96-0005C1 | |
| BRDT(1,2) Bromodomain | 96-0046C1 | |
| BRDT(1) Bromodomain | 96-0006C1 | |
| SMARCA4 Bromodomain | 96-0060C1 | |
| TAF1L(2) Bromodomain | 96-0058C1 |
SPRINTer™ Cell Line
Protein Turnover Detection을 위한 세포 기반 분석이 가능한 Cell Line으로, 간편한 실험 프로토콜과 빠른 실험 결과 도출이 특징입니다.
| Target | Description | Cat. No. |
| BRD4 | SPRINTer™ HCT-116 BRD4 Protein Turnover Biosensor Cell Line | 91-1004C047 |
| BRD4 | SPRINTer™ K562 BRD4 Protein Turnover Biosensor Cell Line | 91-1002C042 |
서비스 절차
서비스 문의