Obesity 서비스
비만치료제 개발에 활용 가능한 Eurofins Discovery의 서비스 패널
| Eurofins DiscoverX(Eurofins Discovery) 공식 대리점
생체의 Physiological process에서 중요 역할을 하고 있다고 알려진 GPCRs 중에서, Obesity의 Development와 Progression에 연관 되어있다고 알려진 타겟들을 대상으로 β-arrestin, Second messenger, Dimerization assay를 Agonist 또는 Antagonist 모드로 진행하는 서비스입니다. Dose response에 따른 IC50 결과값을 통해 Obesity 타겟에서 약물의 효과를 확인할 수 있습니다.
서비스 종류 및 샘플 준비 방법
| 서비스 유형 | obesityLITE Panel |
| Target 수 | 13 |
| Assay수 | 25 |
| 실험농도 | 선택 가능 |
| 농도 개수 | 10개 농도(3 fold dilution) |
| 반복실험횟수 | Duplicate |
| Sample Volume | 실험할 농도의 1000X stock으로 75ul |
| TAT | 22 Days |
| 실험 모드 | Agonist & Antagonist |
| 서비스 장소 | Fremont, CA USA |
서비스 상세
| FAMILY | NAME | ITEM NUMBER | PROTEIN NAME |
| GPCR | GIP Human Glucagon GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2059AG | GIP |
| GPCR | CT Human Calcitonin GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2114AG | CT |
| GPCR | AMY3 (CT/RAMP3) Human Calcitonin GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2116AG | AMY3 (CT/RAMP3) |
| GPCR | CT Human Calcitonin GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2245AG | CT |
| GPCR | AMY3 (CT/RAMP3) Human Calcitonin GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2276AG | AMY3 (CT/RAMP3) |
| GPCR | Glucagon Human Glucagon GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2306AG | Glucagon |
| GPCR | GIP Human Glucagon GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2308AG | GIP |
| GPCR | GLP-1 Human Glucagon GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2309AG | GLP-1 |
| GPCR | CCK1 (CCKA) Human Cholecystokinin GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2138AG | CCK1 (CCKA) |
| GPCR | GHSR Human Ghrelin GPCR Cell Based Antagonist Arrestin LeadHunter Assay – US | 86-0001P-2164AN | GHSR |
| GPCR | Glucagon Human Glucagon GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2165AG | Glucagon |
| GPCR | GLP-1 Human Glucagon GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2166AG | GLP-1 |
| GPCR | MC4 Human Melanocortin GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2189AG | MC4 |
| GPCR | Y2 Human Neuropeptide Y GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2198AG | Y2 |
| GPCR | Y4 Human Neuropeptide Y GPCR Cell Based Agonist Arrestin LeadHunter Assay – US | 86-0001P-2199AG | Y4 |
| GPCR | OX1 Human Orexin GPCR Cell Based Antagonist Arrestin LeadHunter Assay – US | 86-0001P-2205AN | OX1 |
| GPCR | OX2 Human Orexin GPCR Cell Based Antagonist Arrestin LeadHunter Assay – US | 86-0001P-2206AN | OX2 |
| GPCR | MC4 Human Melanocortin GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2326AG | MC4 |
| GPCR | Y2 Human Neuropeptide Y GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2337AG | Y2 |
| GPCR | Y4 Human Neuropeptide Y GPCR Cell Based Agonist cAMP LeadHunter Assay – US | 86-0007P-2338AG | Y4 |
| GPCR | CCK1 (CCKA) Human Cholecystokinin GPCR Cell Based Agonist Calcium Flux LeadHunter Assay – US | 86-0030P-2138AG | CCK1 (CCKA) |
| GPCR | GHSR Human Ghrelin GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay – US | 86-0030P-2164AN | GHSR |
| GPCR | OX1 Human Orexin GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay – US | 86-0030P-2205AN | OX1 |
| GPCR | OX2 Human Orexin GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay – US | 86-0030P-2206AN | OX2 |
| Cell Surface (Other) | LEPR/LEPR Human Cytokine Cell Based Agonist Dimerization LeadHunter Assay – US | 86-0020P-2661AG | LEPR |
서비스 절차
서비스 문의